multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

Christina Applegate has reportedly been hospitalized in Los Angeles since late March, amid the Emmy winner’s enduring battle with multiple sclerosis. —Jami Ganz, New York Daily News, 17 Apr. 2026

The price hikes include expensive gene therapies, cancer medications and multiple sclerosis drugs. —Berkeley Lovelace Jr, NBC news, 16 Apr. 2026

The price hikes include expensive gene therapies, cancer medications, and multiple sclerosis drugs. —Ed Silverman, STAT, 16 Apr. 2026

And in multiple sclerosis, that's exactly what happens. —Marcy Thompson, Scientific American, 16 Apr. 2026

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor